Endocrine Abstracts

Purposes: To investigate the effects of α-lipoic acid (ALA) on diabetic dyslipidemia, endothelial dysfunction, levels of adiponectin and proinflammatory mediators in combination therapy of patients with ischemic heart disease (IHD) and type 2 diabetes mellitus (T2DM).Methods: We examined 40 patients with IHD and T2DM (19 males, age 60.5±4.7 years). Baseline characteristics of patients included history of IHD (7.2±2.3 years), T2DM (4.7&#177...

Purposes: To investigate effects of combination therapy with fenofibrate and α-lipoic acid (ALA) on atherogenic dyslipidemia, which determines the residual vascular risk and endothelial dysfunction, levels of proinflammatory mediators in patients with ischemic heart disease (IHD) and type 2 diabetes mellitus (T2DM).Methods: We examined 42 patients with IHD and T2DM (19 males, age 60.5±4.7 years). Baseline characteristics of patients included hi...

Objectives: Diabetes mellitus (DM) is an independent predictor of new onset heart failure (HF) and adverse outcomes among patients with already existing HF. However mechanisms leading to impaired cardiac performance due to DM are still unclear.The purpose of investigation was to assess the influence of cardiac dyssynchrony (DYS) on systolic and diastolic function in patient with type 2 diabetes mellitus (T2DM) with concomitant stable coronary artery dise...